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Genetic Diseases WebQuest
A WebQuest for 7th Grade (Science)
Designed by
Pamela Aban
for
J741, Educational Services in Libraries
School of Library and Information
Studies
University of South Carolina at
Columbia
Fall 2004
Amanda LeBlanc, Instructor
Image from www.doegenomes.org
Introduction
You are a medical intern who has a patient that has come
to you not feeling well. Based on the patient's symptoms, you will
make a diagnosis of the patient's disease. Once you have diagnosed
and researched the disease, you will then report your findings to your
fellow colleagues at the Genetic Disease
Conference for medical interns.
At the conference you will
learn about a wide variety of genetic diseases and disorders. You
will gain an understanding that mutations can affect the function of
an organism and can result in diseases and how those diseases are inherited.
You will hopefully develop a compassion for people with diseases.
You will also collaborate on possible ideas that could lead to
further scientific research for these diseases.
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Task
1. As a medical intern, you have a patient in
your clinic who is ill. Based on the case study with the
symptoms provided to you by the Chief Resident, your job as a medical
intern is to learn what you can about these symptoms and diagnose
this disease.
2. Once you have diagnosed the disease that
this patient has, you will investigate various aspects of the genetic
disease or disorder and record your findings. You will need to
record the information that you found regarding this disease in your
scientific journal
pdf .
3. You will then create a presentation using
MS PowerPoint to present the facts you learned in Steps 1 and 2 to
your fellow colleagues at a medical conference, as doctors often
do to share medical information.
4. After the presentations and based on what
you learned at the conference, you will collaborate with your colleagues
on future research ideas and questions. You will help formulate
questions for future study ideas for these genetic diseases.
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Process
1. First you will be given a case study prepared
by your Chief Resident on a patient who is ill in your clinic.
Each intern will receive a different case study. (See blank sample here).
2. Each intern will read and review their case
study carefully for clues based the patient description and symptoms.
Based on the information provided on the case study, visit the following
site in order to explore the various genetic diseases and their symptoms.
This will help you to make your diagnosis.
Make Your Diagnosis
Glossary1 Glossary
2 for clarification of terms
3. Once you have diagnosed what you believe
the disease to be, please consult and confirm your diagnosis with
your Chief Resident before proceeding further.
4. Once the disease confirmation has been made,
conduct a thorough investigation into that particular genetic
disease.
5. Please print and record your research in
your scientific journal
pdf as
a way to guide and organize your research. For your research,
you will need to identify the:
- symptoms
- causes
- incidence
- tests and screening
- treatments
- how it is inherited
- facts and theories
- expected quality of life for the patient
- additional thoughts and questions
6. In order for you to conduct your research, you
have been provided with the following Internet resources:
Sites with Various Genetic Disease Information:
Genetics
Home Reference: The U.S. National Library of Medicine provides
a service that includes this guide to understanding genetic conditions.
Includes information on what is new, a handbook, glossary, resources,
a search box, and the browse option for exploring more information on
each disease.
Genetic
Information and Patient Services: a non-profit organization
providing information on the Internet about genetic disorders and birth
defects. Includes definitions of disorders, resources, and a glossary.
Genetic Disorders:
The National Institutes of Health, National Human Genome Research
Institute provides an overview of genetic diseases and information on
some specific genetic disorders.
Blazing the
Genetic Trail, Howard Hughes Medical Institute: Information
on why there are so many errors in our DNA, how genetic disorders are
inherited, and how to conquer a genetic disease.
Genetic and
Rare Conditions Site, U of Kansas Medical Center: Includes
advocacy and support groups, information on genetic conditions and birth
defects, and national and international organizations.
Sites for Specific Genetic Diseases:
7. Each intern will also need to visit your school
or local public library and use (1) print resource to obtain additional
information on your disease. Your print resource may be an encyclopedia,
a book, or a magazine.
8. Remember to always cite your sources that
were used for your research and presentation. There is a space
at the bottom of your scientific
journal pdf for recording citations. If you need help, following
one of these links:
OSLIS
Citation Maker or
NoodleBib 5.
Citation Examples:
Book Citation: Author's Last Name, First Name Middle
Name. Title of Book. City of Publication: Publisher's Name, Year of Publication.
Magazine Citation: Last Name, First Name Middle Name.
"Title of Article." Name of Magazine. Date of Publication: Page Numbers of Article.
Webpage Citation: Last Name, First Name Middle Name.
"Specific Page or Article Title." Title of Entire Web Site. Date
Web Page Was Last Revised. Sponsoring Organization. Date You Read
It <URL>.
9. Once you have investigated your genetic disease,
you will create a MS PowerPoint presentation (guidelines here
pdf ) to present to your fellow medical interns at the Genetic Disease Conference.
This will be an opportunity for you to give an oral and multimedia
presentation using graphics on the results of your research.
Professionals often meet at conferences in order to present and share
ideas and discoveries with their colleagues.
10. As part of the conference and following
the genetic disease presentations, you will participate in a brainstorming
session with other young, bright, and innovative medical interns
on ideas that warrant further investigative research into possible
cures or treatments for these various genetic diseases.
11. Select an intern or have the Chief Resident
record the ideas. Also, as Part II of this session, record
questions that you would like to ask a genetic counselor or genetic
researcher in order to further your understanding of the diseases.
12. For the disease that you diagnosed and investigated,
what would you recommend to the family of the patient based on what
you have learned? After consulting with your fellow colleagues
if needed,
- What tests or screening would you suggest
to confirm the diagnosis?
- Would you recommend further testing of
the parents or siblings?
- How would you explain to the family how
the disease is inherited?
- What treatment would you suggest as the
best one?
- Do you know anyone personally with this
type of inherited disease?
- What is the prognosis for this patient?
- Once you have learned what it is like living with the
disease, do you have any ideas on how to make life easier for this
patient?
Remember, as medical interns, it is important to use
compassionate and caring attitudes in relaying information to the family
and patient.
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Evaluation
Research Rubric
pdf
PowerPoint Rubric
pdf
Presentation Rubric
pdf
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Conclusion
What an amazing group of medical interns you
are! You have successfully diagnosed, researched, and creatively
presented your findings to your colleagues. You have learned a great
amount of information about other genetic diseases, as well as using
research skills, and collaborating and sharing of information. You
have developed a sense of compassion for your patients by learning about
what life is like for each patient and the difficulties they must endure.
This will help you become an informed patient, family member, or perhaps,
one day, a future physician. You have done a wonderful job of developing
ideas for future research investigations into these diseases.
Maybe one of you will find a cure for one of these genetic diseases
one day!
If you would like to learn more, you might want to
check out the following links:
Gene
Therapy Related Links: The Gene School '99 is an educational site
that explores genetic science. Includes gene therapy information and
links, ethics, fundamental information, a glossary, and interactive games
and experiments.
Human
Genome Project: The National Institutes of Health, National
Human Genome Research Institute includes information entitled, "All
About the Human Genome Project."
Ethics
of Genetic Testing: Access Excellence @ The National Health
Museum provides an overview on genetic screening and ethics. Includes
some genetic diagnoses available, along with the incidences and nature
of some genetic diseases.
How Stuff Works: Information on How the Cell Works,
including enzymes, proteins, DNA, genetic diseases, and biotechnology.
Includes links to more information.
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Credits
I would like to say a special thank you to Mrs. Linda
Strother, 7th grade Gifted Science teacher at Lakeside Middle
School in Evans, Georgia, for all of her help and suggestions while
collaborating on this project. I would also like to thank my
professor at the University of South Carolina, Mrs. Amanda LeBlanc
for her guidance, and to Mrs. Kim Isiminger, School Media Specialist
at Lakeside Middle School, for all of her help.
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Specific Diseases National Websites
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4 October 2004. Available URL: http://www.alz.org/
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Foundation. 15 October 2004. Available URL: http://www.hemophilia.org/home.htm
"Breaking the Sickle Cycle." 14 March 2004. Sickle Cell Disease
Association of America, Inc. 15 October 2004. Available
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"Cooley's Anemia Foundation: Leading the Fight Against Thalassemia."
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4 October 2004. Available URL: http://www.cff.org/home/
"Fraxa Home Page." 2004. The Fragile X Research Foundation. 15
October 2004. Available URL: http://www.fraxa.org/
"HDSA Home Page." Huntington's Disease Society of America.
15 October 2004. Available URL: http://www.hdsa.org/
"The National Down Syndrome Society Web Site." 2004. National Down
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"National PKU News: News and Information about Phenylketonuria."
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Foundation. 15 October 2004. Available URL: http://www.nf.org/
"NMF Home Page." 2004. The National Marfan Foundation. 15
October 2004. Available URL: http://www.marfan.org/nmf/index.jsp
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Hemochromatosis Society. 15 October 2004. Available URL: http://www.americanhs.org/
"Welcome to the National Tay-Sachs & Allied Diseases Association,
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Images
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